Biology

 

Cardiovascular & Metabolic Diseases 中文 (CN version)


Obesity

  • Acute food intake, chronic food intake and BW studies, breeding or establishing DIO mice, multiple clinical readouts

Diabetes

  • oGTT (mouse/rat), ipGTT (mouse/rat), ivGTT (rat), glucosuria
  • Chronic efficacy studies in db/db and other hyperglycemic models, chronic efficacy studies for improvement of insulin sensitivity
  • DIO/STZ mice

Dyslipidemia

  • Acute lipid tolerance
  • Chronic studies to monitor TG, cholesterol

Hypertension

  • Blood pressure measurement in telemetrized rats
  • (Na/K) diuresis

Nephropathy

  • Proteinuria, natriuresis
  • Podocyte-induced kidney injury
  • Cisplatin-induced kidney injury

Thrombosis

  • Rat arteriovenous shunt model
  • Rat tail bleeding model