Oncology

 

CRISPR 中文 (CN version)


CRISPR/Cas9 Gene Editing Platforms

  • Generation of cell lines with CRISPR-mediated gene knockout and knockin
  • Genome-wide screening for target identification and validation
  • Human and mouse CRISPR knockout libraries
  • Human CRISPR activation libraries
  • Fast generation of GEMMs for genetic disease

CRISPR/Cas9 for target validation

  • Target validation in cells or micein combination with other tools such as lentiviral gene overexpression, RNAi knockdown

20150410-19

Case

Gene knockout of gene X in MDA-MB-231 by CRISPR/Cas9

20150414-11

CRISPR/Cas9 based genome-wide knockout screening

  • To understand drug resistance mechanism and identify new targets

20150413-3

20150413-2